Clinically Proven Natural Anti-Inflammatory

Main active ingredient, Omega-3, has been clinically proven to reduce pain associated with inflammation

2.5 grams daily or more of Omega-3 fatty acid supplementation, such as that found in OMAPURE™, has been shown repeatedly in clinical trials to produce anti-inflammatory benefits. 

The clinical research today is strongest for rheumatoid arthritis with 13 double-blind, placebo-controlled studies1 showing results such as an improvement in patient’s overall assessment of pain, a reduction in tender joint count, a reduction in morning stiffness, and so on.

Below are some of the conclusions from several of the studies:

Non-randomized, double-blind, placebo controlled study2:

“The results of the present study confirm and expand upon our original finding that dietary fish oil ingestion produces clinical benefits in patients with active rheumatoid arthritis.”  

Randomized, double-blind, placebo controlled study3:

“Our study shows significant improvement of clinical disease variables in patients with rheumatoid arthritis during dietary fish oil supplementation.”  

 Randomized, double-blind, placebo controlled study4:

“We conclude that the clinical benefits of dietary supplementation with Omega-3 fatty acids are more commonly observed in patients consuming higher dosages of fish oils for time intervals that are longer than those previously studied.”  

Randomized, 12 month, double-blind, placebo controlled study5:

“Findings of this double-blind study of the effect of fish oil supplementation in patients with active RA confirm the positive results obtained in previous short-term studies and extend these observations to the long-term follow-up of 1 year of treatment.”   

Randomized, double-blind, placebo controlled study6:

“We have demonstrated that patients with active rheumatoid arthritis who consume high-dose fish oil supplements exhibit improvements over baseline in multiple clinical parameters.”  

Meta-analysis study7:

“The meta-analysis demonstrated that dietary fish oil supplementation for 3 months significantly reduced tender joint count and morning stiffness as compared with heterogeneous dietary control oils.”  

OMAPURE™’s formulation closely mirrors a randomized double-blind placebo controlled study published in the highly regarded peer reviewed medical journal, Arthritis & Rheumatism.5  OMAPURE™ contains the same amount of EPA (the main anti-inflammatory ingredient in Omega-3) used in this very successful clinical trial.  

Below are some of the positive results from the clinical trial:

-- > Patients reported a significant drop in disease severity:

A negative % change from baseline means that the patient reported a drop in severity of disease activity.

The high dose (as found in OMAPURE™) demonstrated superior effect compared to the low dose (as found in most Omega-3 brands) and placebo.  Also noteworthy is that patients who stuck with the high dose Omega-3 therapy for 12 months were able to realize an additional 50% improvement above and beyond the superior results they already obtained by the third month.

-- > Patients and physicians noticed measurable improvement in pain:

-- > About 50% of patients reported a reduction in NSAIDs (non-steroidal anti-inflammatory drugs) and DMARDs (disease modifying anti-rheumatic drugs):

NSAIDs side effects can be severe and include morbidity and mortality.  It is no small feat that about half of the patients were able to reduce their use of NSAIDs and DMARDs by using a natural anti-inflammatory supplement.   The results from this particular clinical trial are not atypical.  Please read about several other clinical studies demonstrating (at the appropriate dose) Omega-3’s ability to reduce or eliminate NSAID use.

OMAPURE™’s formulation of 1.7 grams of EPA and 2.6 grams of Omega-3 closely mirrors the same treatment given the patients in the above double-blind placebo controlled trial.   As highlighted above, these patients showed a noticeable improvement in overall global assessment, a reduction in pain, and the potential to decrease dangerous NSAID use – all without significant side effects.

Omega-3 is a proven, safe, and natural anti-inflammatory.   OMAPURE™ has been specifically formulated with similar Omega-3 doses used in trials that have shown significant pain relief.  Order OMAPURE™ today.

Another OMAPURE™ Advantage – Exceptional Value >>

Many of the placebo-controlled trials of fish oil in chronic inflammatory diseases reveal significant benefit, including decreased disease activity and a lowered use of anti-inflammatory drugs.
-Journal of the American College of Nutrition, 2002


  1. Cleland LG, James MJ: Rheumatoid arthritis: adulthood - prevention.  The Medical Journal of Australia 2002; 176 (11 Suppl): S119-120. 
  2. Kremer JM, Jubiz W, Michalek A, Rynes RI, Bartholomew LE, Biagaouette J, et al: Fish oil fatty acid supplementation in active rheumatoid arthritis.  A double-blinded, controlled, crossover study.  Ann Intern Med 1987 106:497-503.    Abstract
  3. van der Tempel H, Tulleken JE, Limburg PC, Muskiet FA, van Rijswijk MH: Effects of fish oil supplementation in rheumatoid arthritis.  Ann Rheum Dis 1990 Fe; 49(2):76-80.   Abstract
  4. Kremer JM, Lawrence DA, Jubiz W, DiGiacomo R, Rynes R, Bartholomew LE, Sherman M: Dietary fish oil and olive oil supplementation in patients with rheumatoid arthiritis: clinical and immunologic effects.  Arthritis Rheum 1990 33:810-820.   Abstract
  5. Geusens P, Wouters C, Nijs J, Jiang Y, Dequeker J.  Long-term effect of n-3 fatty acid supplementation in active rheumatoid arthritis: a 12 month double blind controlled study.  Arthritis Rheum 1994; 37:824-9.   Abstract
  6. Kremer JM, Lawrence DA, Petrillo GF, Litts LL, Mullaly PM, Rynes RI, Stocker RP, Parhami N, Greenstein NS, Fuchs BR, et al.: Effects of high-dose fish oil on rheumatoid arthritis after stopping nonsteroidal antiinflammatory drugs.  Arthritis Rheum 1995 Aug; 38(8):1107-14.    Abstract
  7. Fortin PR, Lew RA, Liang MH, Wright EA, Beckett LA, Chalmers TC, Sperling RI: Validation of a meta-analysis: the effects of fish oil in rheumatoid arthritis.  J Clin Epidemiol 1995 Nov; 48(11): 1379-90.    Abstract